Download Accurate Results in the Clinical Laboratory. A Guide to by Amitava Dasgupta PDF

By Amitava Dasgupta

This sensible, easy-to-use advisor, named to Doody’s center Titles 2013, addresses interference matters in all laboratory checks, together with sufferer epigenetics, means of specimen assortment, enzymes, biomarkers. Clinicians and laboratory scientists can accordingly depend on one reference which speaks to either their wishes of actual specimen research and optimum sufferer care.

Erroneous medical institution and pathology laboratory effects may be complicated and challenging, specifically in acute care occasions. whereas a few elements growing interference, may be pointed out within the laboratory, detecting many others is frequently depending on medical info unavailable to the laboratory scientists or pathologists. hence, clinicians needs to develop into trained in settling on such inaccurate stories, and dealing with pathologists and laboratory scientists so one can comprehend the resource of such interferences, right the consequences, after which come to a decision what plan of action needs to be for correct sufferer management.

  • Named to Doody’s middle Titles 2013, a suite improvement software for health and wellbeing sciences libraries of all sizes, by means of Doody Enterprises
  • Practical info for either clinicians and laboratory scientists, awarded within the type of tables and charts for simple reference
  • Focus on diversity and assets of interferences instead of information of toxicologic mechanisms that are good lined in toxicology textbooks
  • Covers interferences throughout endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing

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Additional resources for Accurate Results in the Clinical Laboratory. A Guide to Error Detection and Correction

Example text

Iodine compounds have been noted to affect some assays and probably should be avoided for chemistry studies [51]. In particular, ACCURATE RESULTS IN THE CLINICAL LABORATORY URINE COLLECTION, TIMING, AND TECHNIQUES povidone iodine can falsely elevate potassium, phosphorous, and uric acid in specimens collected by skin puncture [51]. Anticoagulants For coagulation assays, the proper ratio of blood to citrate is critical. For this reason, the tube must be filled to the required volume. Excess air allowed to enter the tube will limit the quantity of blood, thereby perturbing this ratio [51].

Clin Chem 2006;52:1627À8. Rodushkin I, Odman F. Assessment of the contamination from devices used for sampling and storage of whole blood and serum for element analysis. J Trace Elem Med Biol 2001;14:40À5. Shah VP, Knapp G, Skelly JP, Cabana BE. Interference with measurements of certain drugs in plasma by a plasticizer in Vacutainer tubes. Clin Chem 1982;28:2327À8. Drake SK, Bowen RA, Remaley AT, Hortin GL. Potential interferences from blood collection tubes in mass spectrometric analyses of serum polypeptides.

With the foreskin still retracted, allow the bladder to partially empty. This will serve to flush bacteria and other material from the urethra. Finally, collect a resulting “midstream” sample for testing. The technique for females is similar: Separate the labia minora and clean the urethral meatus with mild soap followed by rinsing. Sterile cotton balls are commonly used for this purpose. Continue holding the labia minora apart and partially empty the bladder. Finally, collect a midstream sample for testing.

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