Download ABC Proteins: From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher PDF

By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins

ABC Proteins is an in-depth, updated research of all that's recognized in regards to the topic to this point. It discusses and compares evolution, biology and mechanism of motion of all identified ABC proteins, together with the 1st structural experiences in addition to medical implications. will probably be valuable to someone attempting to remain abreast of the newest findings. This publication is bound to develop into a vintage and should on a regular basis be up to date. Key gains* Phylogeny and Evoloution of ABC Transporters* basic elements of the Mechanism of motion of ABC Transporters* Prokaryote ABC Transporters* Non-Mammalian Transporters* Multidrug Transporters* ABC Transporters, Physiological Roles and Human illness* complete colour all through

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And El Solh, N. (1992) Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics. Gene 117, 45–51. , et al. (1997) Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science 277, 1805–1807. , Romano-Spica, V. and Dean, M. (1998) 27 28 ABC PROTEINS: FROM BACTERIA TO MAN A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.

1999) Glucose transport in the extremely thermoacidophilic Sulfolobus solfataricus involves a high-affinity membraneintegrated binding protein. J. Bacteriol. 181, 4285–4291. T. M. (1989) Identification of a gene linked to Rhizobium meliloti ntrA whose product is homologous to a family of ATP-binding proteins. J. Bacteriol. 171, 1932–1941. , Loncle, V. and El Solh, N. (1992) Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics.

152, 331–340. J. F. (1998) The Escherichia coli ATP-binding cassette (ABC) proteins. Mol. Microbiol. 28, 5–13. , Furuya, K. C. (1996) The Streptomyces peucetius drrC gene encodes a UvrA-like protein involved in daunorubicin resistance and production. J. Bacteriol. 178, 3238–3245. , Martinoia, E. A. (1998) AtMRP2, an Arabidopsis ATP binding cassette transporter able to transport glutathione S-conjugates and chlorophyll catabolites – functional comparisons with atMRP1. Plant Cell 10, 267–282. B. D.

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